ABSTRACT
Episodic hypersomnia, compulsive excessive eating and erotic behaviour, with schizophreniclike mental symptoms are the hallmarks of the rare KleineLevin syndrome. Many patients may not necessarily fulfill minimum criteria described for diagnosis. We report a 19 years young man with incomplete presentation the KleineLevin syndrome and briefly reviewed the most relevantaspects of this disorder, its epidemiology, clinical symptoms and complementary diagnostic examinations. Known therapeutic options and prognosis are also discussed.
Subject(s)
Humans , Male , Adult , Disorders of Excessive Somnolence , Kleine-Levin Syndrome , Sleep Disorders, IntrinsicSubject(s)
Adult , Humans , Practice Guidelines as Topic/standards , Stroke , Chile , Evidence-Based Medicine/standards , Stroke/diagnosis , Stroke/therapyABSTRACT
Background: Hispanics have a greater incidence of stroke and prevalence of intracranial atherosclerosis than whites. Aim: To study the prevalence of extracranial atherosclerosis among patients admitted to a hospital with an ischemic stroke. Material and methods : A prospective study in stroke patients admitted to a Neurology ward in a University Hospital. All were subjected to a CT scan, carotid duplex-Doppler ultrasonographic examination with Doppler measurement of blood flow velocity, permeability and plaques. Cardiac emboli were searched with transthoracic and transesophagic echocardiography. Results: One hundred ten patients (39 women), aged 67.5ñ11.4 years old were studied. Stroke was atherothrombotic in 46 (41.8 percent), embolic in 30 (27.3 percent), lacunar in 27 (24.6 percent) and of other type in 7 (6.4 percent). Ninety two patients (84.4 percent) had high blood pressure, 38 percent had high cholesterol levels, 35 percent had a cardiac disease and 26 percent were smokers. Thirty five subjects (31.8 percent) had a normal carotid ultrasonography, 46 (41.8 percent) had mural plaques, 16 (14.5 percent) had multiple plaques without occlusion, 13 (11.8 percent) had a partial occlusion and 7 (6,4 percent) had a total occlusion. Logistic regression analysis disclosed no significant relationship between stroke types and carotid atherosclerosis. Age was the only significant predictor for carotid atherosclerosis. Conclusions: The prevalence of severe carotid atherosclerosis in this group of stroke patients was less than expected